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4 edition of Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines found in the catalog.

Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines

Arnold Henning Seto

Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines

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  • 16 Currently reading

Published by National Library of Canada in Ottawa .
Written in English


Edition Notes

Thesis (M.Sc.) -- University of Toronto, 1994.

SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
FormatMicroform
Pagination2 microfiches : negative. --
ID Numbers
Open LibraryOL17063398M
ISBN 100315963581
OCLC/WorldCa222168011

  Non nghen trong thai ky - nausea and vomiting of pregnancy - ACOG guideline 1. VOL. , NO. 1, JANUARY OBSTETRICS & GYNECOLOGY e15 Nausea and Vomiting of Pregnancy Nausea and vomiting of pregnancy is a common condition that affects the health of a pregnant woman and her fetus.


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Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines by Arnold Henning Seto Download PDF EPUB FB2

OBJECTIVE: Conflicting reports on potential risks of antidepressant exposure during gestation for the infant have been reported in the literature. This systematic review and meta-analysis on immediate neonatal outcomes were conducted to clarify what, if any, risks are faced by infants exposed to antidepressants in by: To determine the relative risk for major malformations associated with antihistamine (H1 blockers) exposure in the first trimester of pregnancy, a literature search of all studies examining the association between antihistamines and major malformations for the period to Cited by: The Risk of Adverse Pregnancy Outcome After First Trimester Exposure to H1 Antihistamines: A Systematic Review and Meta-Analysis Article in Drug Safety 40(2) November with 55 Reads.

The maternal, fetal and neonatal effects in pregnant women using chronic corticosteroids are reviewed. The question as to whether the standard course of antenatal corticosteroids is necessary if.

Exposure to drugs during pregnancy has the potential to harm offspring. Teratogenic effects are the most feared adverse outcomes in newborns; however, a wide spectrum of less known, usually reversible and often acute, neonatal adverse events can also occur due to drug intake by mothers during pregnancy, particularly in close proximity to by: 7.

The investigators performed a systematic review of clinical literature and meta-analysis of retrospective, case-control studies to assess the effects of methamphetamine exposure during pregnancy.

H1 antihistamines are used for the treatment of nausea and vomiting during pregnancy as well as the symptomatic relief of asthma, urticaria, allergy, and the common cold.

Although they are overall felt to be safe during pregnancy, recently several studies have challenged this assumption, as millions of women are exposed to them in the first trimester. Following the guidelines of PRISMA, a Cited by: PRISMA-P guideline was followed in the present systematic review and meta-analysis ().A computerized database search was carried out on databases PubMed, PMC, MEDLINE, EMBASE, SCOPUS, and Google Scholar by May with search terms of selective serotonin reuptake inhibitors, SSRI, autism spectrum disorders, ASD, pregnancy, childhood, children, and neurodevelopment in order to identify Cited by:   Objective.— To estimate the incidence of serious and fatal adverse drug reactions (ADR) in hospital Sources.— Four electronic databases were searched from to Study Selection.— Ofwe selected 39 prospective studies from Cited by: A meta-analysis of adverse perinatal outcomes in women with asthma VE Murphy,a JA Namazy,b H Powell,a,c M Schatz,d C Chambers,e J Attia,f PG Gibsona,c a Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines book for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia b Department of Allergy-Immunology, Scripps Clinic, San Diego, CA, USA c Department of Respiratory Cited by: with increased risk of adverse perina-taloutcomes,birthspacingmightthen be considered an intervention to pre-ventsuchadverseoutcomes,mainlyin the developing world.

Therefore, we performedasystematicreview,includ-ing meta-analysis, of the relationship between birth spacing and the risk of adverse perinatal outcomes that pro. Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H 1 or H 2).H 1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions.

We will review classes of antihistamines (H 1 antagonists) and the relationship between Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines book antihistamines and specific birth by: 1. The relationship between maternal and infant dietary exposures and risk of Exposure variables were recorded according to the original studies, studies, case-control studies and cross-sectional surveys.

Where meta-analysis was deemed inappropriate due to differences in population, exposure/intervention or outcome, or where meta-analysis. Introduction. The safety of drug prescribing has become a highly visible topic in adult medicine, due in part to research suggesting that there are important ADRs caused by commonly used medications [].Much less attention has been focused Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines book neonates, infants, children and adolescents [2, 3].Paediatric patients constitute a vulnerable group with regard to rational drug prescribing since many Cited by: Meta-analysis of adverse neonatal effects due to maternal exposure to antihistamines book PUBLIC ATTENTION is currently focused on adverse drug reactions (ADR) as evidenced by a recent bill passed by the US Senate requiring pharmaceutical companies to provide ADR information to consumers.

1 Heightened interest in ADRs was stimulated by the thalidomide tragedy in the s. 2 To obtain an accurate estimate of ADR incidence in hospital patients, prospective studies were done.

[Epub ahead of print] Epidemiologic studies suggest that maternal ambient air pollution exposure during critical periods of pregnancy is associated with adverse effects on fetal development.

In this work, we introduce new methodology for identifying critical periods of development during post-conception gestational weeks where elevated.

for low birth weight were (fixed-effects model, 95% CI, –) and (random-effects model, 95% CI, –). In stratified analyses, the effect of low birth weight on childhood asthma was strong, particularly in studies conducted in Europe, those with a small sample size, and those published by: Keywords: adverse drug reactions, child, meta-analysis, prospective studies, systematic review Introduction The safety of drug prescribing has become a highly visible topic in adult medicine, due in part to research suggesting that there are important ADRs caused by commonly used medications [1].

Much less attention has been focused onCited by: /or vomiting could be the primary presenting illness or simply a symptom of a more complex etiology. Although there is a wide variety of pharmacotherapeutic options in the armamentarium to treat these conditions, very few consensus recommendations exist to help guide the use of antiemetic agents in the ED, leading to wide variability in medication use.

Contributing to these variations in. Seven studies used the term "adverse drug event" 9,14,19,21,23,30,31, while two used "adverse drug reaction" 26,33, based on the concept of harm caused to the patient due to use of the drug in the therapeutic context, while four 9,14,21,30 defined the event as any injury, large or small, caused by the therapeutic use (including non-use) of a.

Exposure to sunlight during the day, as well as darkness at night, helps to maintain a healthy sleep-wake cycle.

Establish a regular relaxing bedtime routine. A regular nightly routine helps the body recognize that it is bedtime.

This could include taking a warm shower or bath, reading a book, or light stretches. The American Academy of Allergy, Asthma & Immunology is the largest professional medical organization in the United States devoted to the allergy/immunology specialty.

The AAAAI represents asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic disease. Immune Globulin Pharmacokinetics Absorption Bioavailability.

Following IM administration of IGIM, serum concentrations of IgG peak within 2 days. Following IV administration of IGIV, there is an immediate post-infusion peak in serum IgG concentrations followed by a biphasic decline.

Following sub-Q administration of immune globulin, peak serum IgG concentrations are. These effects may be additive with other anticholinergic medications in any patient, but the geriatric adult may be more susceptible.[] According to the Beers Criteria, paroxetine is considered a potentially inappropriate medication (PIM) in geriatric patients; avoid use due to the potential for orthostatic hypotension, anticholinergic.

Overall geriatric patients exhibit a greater sensitivity to the effects of drugs that gain access to the CNS. in most cases, lower doses result in adequate response and higher incidence of adverse effects may be seen with standard and high doses.

for example, lower doses of opioids provide sufficient pain relief for older patients, where as. Fetal and infant implications of maternal treatment. Acetazolamide crosses the placenta and has been reported to cause limb defects in rodents.

Similar defects have not been reported in humans and use during pregnancy for glaucoma, intracranial hypertension, and altitude sickness has not shown any other adverse effects on either the fetus or the infant. This contribution consolidates data on international pregnancy rating classifications, including the former US Food and Drug Administration (FDA), Swedish, and Australian classification systems, as well as the evidence-based medicine system, and discusses discrepancies among them.

It reviews the new Pregnancy and Lactation Labeling Rule (PLLR) that replaced the former FDA labeling system with Cited by: 5. Penicillins may cause diarrhea (due to disruption of GI flora), candidiasis, and skin rash in breast-feeding infants.

Small studies assessing adverse events in breast fed infants exposed to antibiotics have found adverse event rates of —% after exposure to amoxicillin. The adverse events reported included diarrhea, rash, and somnolence. The most common acute and chronic AEs that are associated with currently recommended ARV drugs or drug classes are presented in the Management of Medication Toxicity or Intolerance tables.

The tables include information on common causative drugs, estimated frequency of occurrence, timing of symptoms, risk factors, potential preventive measures. Allergic Diseases and Asthma in Pregnancy. Updated: January Posted: March Updated by: Isabella Pali-Schöll, PhD a, Jennifer Namazy, MD b, and Erika Jensen-Jarolim, MD a.

a The interuniversity Messerli Research Institute, c/o Department of Pathophysiology and Allergy Research, Center of Physiology, Pathophysiology and Immunology, Medical University of Vienna, Währinger. Newer Antihistamines May Cause Cognitive Impairment at High Doses By John Schieszer. Physicians are generally told that second-generation antihistamines are causing less cognitive impairment than the first-generation agents, but some of the newer medications may produce impairment if used at or above the recommended doses.

Acne, also known as acne vulgaris, is a long-term skin disease that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and possible scarring.

It primarily affects skin with a relatively high number of oil glands, including the face, upper part of the chest, and cations: Anxiety, reduced self. Background: Gastroschisis, a birth defect characterized by herniated fetal abdominal wall, occurs more commonly in infants born to teenage and young mothers.

Ischemia of the vascular vitelline vessels is the likely mechanism of pathogenesis. Given that chronic stress and violence against women are risk factors for cardiovascular disease we explored whether these may represent risk factors for Cited by: 4.

Adverse pregnancy outcomes after exposure to methylphenidate or atomoxetine during pregnancy Søren Pauli Bro,1 Maiken Ina Siegismund Kjaersgaard,2 Erik Thorlund Parner,2 Merete Juul Sørensen,3 Jørn Olsen,4 Bodil Hammer Bech,4 Lars Henning Pedersen,4,5 Jakob Christensen,6,7 Mogens Vestergaard11Research Unit and Section for General Practice, Department of Public Health.

Ephedrine is a potentially dangerous natural compound; as of the US Food and Drug Administration had received o reports of adverse effects in people using it. [22] Adverse drug reactions (ADRs) are more common with systemic administration (e.g. injection or oral administration) compared to topical administration (e.g.

nasal Pregnancy category: AU: A. Data were collected from cycles after transfer of embryos vitrified on Day 3 (n = ) or Day 5 (n = ) and from cycles after fresh embryo transfer on Day 3 (n = ) or Day 5 (n = ), performed between and at the Centre for Reproductive Medicine of the university hospital UZ e measures were neonatal health in terms of birthweight, small-for Cited by: published over the last four years, all focusing on signal detection of the effects of exposures during pregnancy.

Understanding the role of meta-analysis in maternal-fetal health research. Usually, randomized controlled drug studies cannot include pregnant women due to ethical issues surrounding the fear of potential teratogenic risk Author: Fatma Etwel.

Incidence Of Adverse Drug Reactions In Hospitalized Patients: A Meta- Analysis Of Prospective Looking A Gift Horse In The Mouth: Corporate Gifts Supporting Life Sciences Research Screening For Problem Drinking: Does A Single Question Work.

Ephedrine is a potentially dangerous natural compound; as of the US Food and Drug Administration had received o reports of adverse effects in people using it. [22] Adverse drug reactions (ADRs) are more common with systemic administration (e.g. injection or oral administration) compared to topical administration (e.g.

nasal. Studies have also shown that fetal exposure to maternal depression with or without exposure to an antidepressant also has negative effects on infant health Perinatal toxicity effects like jitteriness, respiratory and feeding difficulties, and sedation have been described in cases of exposure to antidepressants but they are generally thought.

used a random-effects model for meta-analysis"5 similar to the pdf used in the only previous meta-analysis of ADRAds This is the method of choice because it takes into account the heterogeneity of the various studies When combining the incidence of .INCIDENCE OF ADVERSE EFFECTS The actual incidence of adverse effects after the administration of intravascular (IV) contrast media is difficult to determine since similar signs and symptoms may be due to concomitant medications, local anesthetics, needles, catheters, and anxiety, among other things.

Underreporting or variation in the. Methods. In a population-based cohort of children ebook in and and followed through when aged 7 and 8, we estimated relative risks (RRs) of ASD and 95% confidence intervals (CIs) from Cox regression in children exposed to any antidepressant medication during pregnancy, and nine specific antidepressant by: